Institute of Bio-Sensing Technology

Impedance spectroscopy

Impedance spectroscopyA novel technology based on impedance spectroscopy has shown that characteristic, fingerprint changes can be seen in cell culture systems exposed to particular cytotoxic agents. The characteristic changes are thought to be representative of the effect of the cytotoxic agents and can give an indication of the mode of action of that agent on the cells. This technology also shows differences in the spectra between different cell types. Further collaboration to investigate the use of this technology to evaluate cytotoxic effects would be valuable. In addition, other collaborative projects could evaluate differences in impedance spectra of different types of cancer relative to healthy cells or to investigate and develop this technology into an environmental monitoring system.

Lead researchers: Professor Richard Luxton & Professor Janice Kiely

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