Institute of Bio-Sensing Technology

IBST is an initiative of UWE, Bristol

Latest News

» All News

Academic partner profile

Biomedical Physics Group, Exeter University

University of Exeter LogoThe Biomedical Physics Group, headed by Prof Peter Winlove at the University of Exeter, is actively involved in the complementary fields of Biophysics and Medical Physics. Research within the Biomedical Physics Group falls under a number of headings:

Biomedical Electrochemistry

The Biomedical Physics Group maintains a long standing interest in biological electrochemistry, ranging from the use of ultra microelectrodes to monitor metabolism on a cellular scale and ultrafast techniques for the assay of free radicals and short-lived signal molecules to in vivo measurements of tissue oxygenation and perfusion in patients undergoing heart or orthopaedic surgery

Electrochemistry has an established place in medical research and clinical monitoring through instruments such as the blood gas monitor and the "glucose pen" for diabetes monitoring. However, in vivo measurements using microelectrodes implanted into tissue have remained problematical. Much of the work of the Biomedical Physics Group is designed to understand and overcome these limitations.


This includes three principal areas of current research. Model of a red blood cell membraneThe first concerns the physical properties of the extracellular matrix, a major component in tissues such as cartilage, intervertebral disc and blood vessels. The second focuses on the physical properties of the cell membrane and the ways in which membrane changes are involved in diseases such as diabetes. The third area of research, closely related to the others, concerns the vasculature. In addition to studies on the exchange of solutes between blood and the surrounding tissue and experimental and theoretical studies on fluid mechanics, the Biomedical Physics Group is active in the development and application of novel techniques for the study of the microcirculation in vivo.

Physics of Human Perception

Recent advances in functional brain imaging and the current interest in human-computer interactions have resulted in increased attention towards the study of perceptual processes. Research at the Biomedical Physics Group in the physics of human perception focuses on the sense of touch through psychophysics studies and neurophysiology. Projects include investigating strategies for the transmission of temporal, spatial and spatio-temporal information to subjects through specific sites on the skin by means of purpose-built stimulator hardware. This work has applications in sensory substitution and virtual environments, and is being used to gain an insight into musculoskeletal pain at the Peninsula MR Research Centre.

Biomedical Optics

The group is involved in biophysical and materials research in a wide range of biophysical applications, from live cell imaging to ultra sensitive detection of bio-molecules. The Biomedical Physics Group has a variety of optical techniques and complementary contrast modalities at our disposal, including Coherent Antistokes Raman Scattering (CARS) and multiphoton excitation microscopy in the new Multiphoton Imaging and Spectroscopy Laboratory

Biomedical Imaging

Members of the group are involved in the management and use of the University's MRI scanner. Research using this includes functional brain imaging and fundamental research on the ability of MRI techniques to reveal the pathophysiology underlying the major clinical problems of osteoarthritis, osteoporosis and degeneration of the intervertebral disc.


For more information and contact details go the Biomedical Physics Group web pages